SciBase Clinical and Medical Case Reports

Case Report

The Effect of Pneumococcal Polysaccharide Vaccine in Preventing Recurrent Upper Respiratory Infections in an Allergic Child: A Case Report

Sepideh Darougar; Seyed Karen Hashemitari; Masoumeh Mesgarian*

One of the most common causes of pediatric medical visits is recurrent respiratory infections, which may become harmful for physical and mental health of growing children. The most common bacterial respiratory pathogen is Streptococcus pneumoniae, found in the nasopharynx with a potential to cause a broad spectrum of diseases, particularly if children are not immunized against it.

Case Report

Character Meets Anatomy: Ten Times Typical DCIs; Case Report

Jochen D Schipke*

An open (Persistent) Foramen Ovale (PFO) is a known risk factor for the development of Decompression Illnes (DCI) in the context of scuba diving. The typical manifestations of PFO-associated DCI encompass cutaneous and vestibular symptoms. Despite this, the efficacy of PFO closure remains a subject of ongoing debate.

Review Article

Effects of Stress-Induced Neuroendocrine-Immune Interaction on Periodontium: A Review

Surajit Mistry*; Debarati Bhowmick; Indrasri Das; Argha Rudra

This review discusses recent advances in our understanding of the relationships between psychological stress, neuroendocrine-immune system, and periodontitis, including how host stress responses affect immune function, alter the oral microbiome and biofilm formation, and promote disease progression.

Short Commentary

Long-Term Management of Obesity with Once-Weekly Semaglutide: Efficacy and Safety in Clinical Trials

Saad Javed Malik*; Mifrah Rahat khan Sherwani; Filza Rahat Khan

Over 800 million people globally are categorized as obese, defined as having a Body Mass Index (BMI) of 30 or more. About 42% of adults in the US suffer from obesity [1], and the yearly cost of obesity-related medical costs is projected to be $173 billion.

Case Report

From Allergies to ATAK: A Complex Case Report Following Ciprofloxacin Administration

Soorampally Vijay; Bharath Raj Kidambi*; Sriram Veeraraghavan

This case report describes a complex clinical scenario involving a previously healthy middle-aged woman who received ciprofloxacin for acute otitis media and subsequently developed symptoms of allergic hypersensitivity and anaphylaxis. Following an intramuscular adrenaline injection for anaphylaxis, she experienced chest pain

Case Report

Delayed Symptoms of Rodenticide Poisoning in a 16-Year-Old: A Case Report

Mohammadreza Mohammadi; Arman Hakemi*; Alireza Ghassemi Toussi; Bita Dadpour; Reza Mousavi; Anahita Alizadeh Ghamsari

Anticoagulant rodenticides, a key tool in pest control since the 1940s, have undergone significant evolution to overcome resistance and improve efficacy. However, resistance in rodent populations led to the development of second-generation anticoagulants such as Brodifacoum and Difenacoum, which are more potent but pose increased risks to non-target species, including humans.

Short Commentary

Advancements and Challenges in the Application of Machine Learning for Biomedical Diagnostics and Disease Prediction

Atefeh Zarei; Ashkan Farazin*

This review paper delves into the transformative potential and challenges of Machine Learning (ML) in the field of biomedical diagnostics and disease prediction. With the advent of advanced computational models and an ever-increasing availability of biomedical data, ML has the potential to revolutionize diagnostic methodologies, enhance predictive accuracy, and streamline therapeutic interventions.

Case Report

A Case Study of Comorbid Psychogenic Non-Epileptic Seizures and Epileptic Seizures in an Adolescent Female with Depression

He Yangliuqing; Liang Fenrong; Wang Yiming*; Wei Yuhan; Ma Tianpei

Among patients with Psychogenic Non-Epileptic Seizures (PNES), about 10% to 30% have epilepsy, which brings some difficulties in diagnosis. Usually, psychogenic non-epileptic seizures and epileptic seizures occur independently at different points in time, and their performance is similar, but rarely seizures can occur several times in a row.

Short Review

Current Evolution in Target Therapies for Blood Cancers

Mariangela Palladino*

Target therapy represents a significant step forward in the treatment of malignant tumors. These therapies typically address to molecular pathways essential for the growth and replication of neoplastic cells.

Case Report

Endoscopic Closure of Duodenal Perforation using Intracavitary Endoscopic Negative Pressure Therapy

Milan Misovic*; Braig C; Weiner M; Koyyala S; Pielmayer S; Muehldorfer S

Regardless of the cause of a duodenal perforation, operative treatment remains a fundamental therapeutic choice. The endoscopic closure of leaks is helpful only for fresh defects without an accompanying infection and is limited by the size of the defect.