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A 29-year-old pregnant woman was referred to our center at gestational week 21 because of "sudden onset of chest pain for 15 hours"; she experienced retrosternal tearing pain with no radiation, accompanied by vomiting for three times, and the pain had no relief. Ultrasonography revealed aortic root dilatation with aortic regurgitation.
Infants have the highest risk to die from heart failure, one of the most stressful life events in infancy. Moreover, this early life stress may have an impact on growth, neurodevelopment and later cardiovascular risk according the Developmental origins of health and disease (abbreviated DOHaD) approach.
I am writing this letter to bring your concern on "The role of beta-adrenergic receptor on epinephrine-induced metastasis in breast cancer". Breast cancer is one of the most common cancers that affect women globally. Metastasis is a major factor in the morbidity and mortality of breast cancer.
Alcohol use has been linked to the development of cardiac arrhythmias and non-ischemic dilated cardiomyopathy. We describe a case of a 29-year-old male who presented with palpitations and chest pain after binge drinking alcohol. We report the clinical presentation, investigations and outcomes after 6 months of abstinence from alcohol.
Marfan Syndrome is a genetic disorder affecting connective tissue, leading to severe cardiovascular, skeletal, and ocular complications. Early detection is essential to prevent critical outcomes such as aortic aneurysms and dissections. However, traditional diagnostic methods, including advanced imaging and genetic testing, are often expensive and invasive.
A rare instance of infective endocarditis by Streptococcus viridans and Lactobacillus spp in an elderly patient with advanced colorectal cancer, leading to an aortic valve abscess, infectious emboli, and stroke. Our hypothesis is the gastrointestinal tract served as the probable entry route for the bacteria.
The patient admitted to the hospital is a 2-year-old girl with cyanosis. The SPO2 is about 87% (in-room air) across all four limbs. Echocardiography showed Atrial Septal Defect (ASD, 17 mm, Panel A, arrow), ventricular septal defect (VSD, 8.5 mm, Panel B, arrow), and severe pulmonary hypertension (Panel C).
Translational cardiology combines different techniques in order to get a correct diagnosis (precision medicine). In a rare disease called arrhythmogenic left ventricular cardiomyopathy caused by non-desmosonal gene mutations 12-lead ECG and results of genetics were combined and analyzed.
High levels of low-density lipoprotein and cholesterol in the blood have been associated with the development of atherosclerosis. Synthetic forms of sex hormones found in the combined oral contraceptive pill are suspected to affect lipid metabolism.
Bruton tyrosine kinase inhibitors, such as ibrutinib, are medications that are actively used for Chronic Lymphocytic Leukemia (CLL) and several lymphomas. They work by inhibiting Bruton's tyrosine kinase therefore affecting B cell proliferation. Ibrutinib itself is associated with multiple cardiotoxicities including atrial fibrillation, ventricular arrhythmias, heart failure, and bleeding.