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Prostate cancer is the most common form of non-skin cancer in men and the second leading cause of cancer death among them. The estimated incidence of prostate cancer worldwide was 1,414,259 in 2020, making it the fourth most commonly diagnosed malignancy, with the majority of cases seen in those over 65 years of age.
Vibrational Optical Coherence Tomography (VOCT) is a new technique to noninvasively characterize skin cancers. We have previously shown that skin cancers exhibit new mechanovibrational peaks at 80, 130, and 250-260 Hz.
To reveal the memories of elderly people about living with the Human Immunodeficiency Virus. Cross-sectional study, with a descriptive analytical character, a qualitative approach and theoretical-methodological support for the Theory of Collective Memory and the Theory of Social Representations. Carried out with 38 seniors.
Cancer treatment is an area of ongoing concern and requires a great deal of research in order to provide patients and providers with the best possible therapeutic options. Conventional chemotherapeutic agents typically cause serious, unexpected side effects from the harmful consequences of the agents on normal, noncancerous tissues.
Ovarian cancer is the most fatal gynecological cancer worldwide. Oftentimes, the management is challenging in low and middle-income settings. This case demonstrates for the first time a papillary serous adenocarcinoma of the ovary seen in a nulliparous young lady in our hospital, coupled with its associated management challenges.
This study validates novel biological and health systems reliability method, in particular suitable for complex multi-dimensional public health and biological systems, versus the well-established bivariate bio-reliability method, being known to accurately assess bivariate dynamic system's extreme contours.
The widespread use of gold nanoparticles (AuNPs) in many fields has increased; however, their potential effects on embryofetal development have not been explored. This study was designed to investigate the potential effects of different sizes of gold nanoparticles (AuNPs) on maternal and embryo-fetal development in rats.
Rectal Adenocarcinoma (RA) represents more than 90% of rectal tumors, with high global incidence and mortality rates. Treatment includes neoadjuvant therapy, curative surgery, and postoperative adjuvant therapy. Complete Pathologic Response (CPR) signifies the absence of residual tumors and affected lymph nodes.
This work was designed to investigate the possible acute and long-term acute toxicity of intravenous (i.v.) injection of 50 nm gold nanorods (AuNRs) in dogs. Eighteen native dogs were divided into control (n=8); acute toxicity (n=5), and long-term acute toxicity (n=5).
This research expresses the preparation and investigation of methotrexate-loaded PLGA nanoparticles on Glioblastoma Multiforme (GBM). The nanoparticles were prepared by precipitation method which had a mean diameter of 102±5 nm with azeta potential of -26±2 mV. The methotrexate loading was 8.3%.
Cancer includes a broad group of diseases that are characterized by the uncontrolled growth of abnormal cells, which can affect any part of the organism, and according to the World Health Organization (WHO), is one of the leading causes of death worldwide. One of the hallmarks of cancer is the development of metastasis, the main cause of death in more than 90% of cancer patients.
Purpose: The objective of this study is to investigate the changes in CCNG1 and FDXR gene expression during RT in breast cancer patients and associate the observed changes with disease- and therapy-related confounding factors through a non-randomized, controlled, open-trial clinical study of 57 breast cancer patients.